Title: Fabrication of cumin seed oil loaded gliadin-ethyl cellulose nanofibers reinforced with adipic acid for food packaging application
Journal: Food Packaging and Shelf Life
Author: 1,3. Asad Hosseini, 2. Soghra Ramezani, 3. Mahnaz Tabibiazar, 4. Marjan Ghorbani, 5. Hossein Samadi Kafil
Year: 2021
Address: 1. Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran
2. Trita Nanomedicine Research Center, Trita Pharmaceuticals, Zanjan, Iran
3. Faculty of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
4. Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
5. Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
Abstract: In this study, the water-insoluble cumin seed oil (CSO) loaded gliadin (GN)-nanofibers (NFs) mat was prepared in
the presence of ethyl cellulose (EC) and adipic acid (AD) using electrospinning method. The NFs were prepared
with mixing 30 % w/v of GN and 15 %w/v of EC at the ratio of 80:20 v/v and 5%w/v of AD were selected as
optimum formulation based on electrospinning efficiency and SEM images. In the presence of EC, the spinnability
of GN fibers improved. Moreover, in the presence of AD the fibers diameters decreased to 50 % (250 ± 14 nm),
and uniformity enhanced in all formulations. AD acted as hydrogen bond cross-linker between mixed biopolymers
that led to increase in the viscosity of the polymer solutions. The selected formulation was loaded with
the CSO based on 10 %w/v of polymers. Thermal stability of the GN fibers was improved in the presence of EC
and AD based on DSC results. The FTIR results confirmed the hydrogen bond crosslinking between polymers and
AD. Based on antioxidant activities results, the prepared NFs successfully retarded the release of CSO. CSO loaded
NFs showed the strong antibacterial and antifungal activity against Escherichia coli, Staphylococcus aureus, and
Aspergillus flavus. NFs had no significant toxicity on the viability of normal human umbilical vein endothelial cell
(HUVEC). The results of the current study indicated that the prepared NFs mat may have a great potential for
using in active food packaging due to its sustained control release properties for loaded antimicrobial and
antioxidant active agent.
Keywords: Gliadin, Ethyl cellulose, Adipic acid, Cumin seed oil, Nanofibers
Application: Food Technology
Product Model 1: High Voltage Power Supply (HV35POV)
Product Model 2:
URL: #https://www.sciencedirect.com/science/article/abs/pii/S2214289421001228#