Title: Kefiran/poly (vinyl alcohol)/poly (vinyl pyrrolidone) composite nanofibers: fabrication, characterization and consideration of effective parameters in electrospinning
Journal: SN Appl Sci
Author: 1. Fatemeh Mehrali, Hakimeh Ziyadi, Malak Hekmati, 2. Reza Faridi‑Majidi, 3. Mahnaz Qomi
Year: 2020
Address: 1. Department of Organic Chemistry, Faculty of Pharmaceutical Chemistry, Tehran Medical Science, Islamic Azad University, Tehran, Iran 2. Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran 3. Active Pharmaceutical Ingredients Research Center, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.
Abstract: The kefran/polyvinyl alcohol and polyvinyl pyrrolidone nanofbers were efectively fabricated for the frst time using electrospinning of poly(vinyl alcohol), poly(vinyl pyrrolidone) and kefran blend solution. The efect of solution parameters, such as kefran concentration and poly(vinyl alcohol)/poly(vinyl pyrrolidone) mixing ratio, were considered. The parameters’ effects, such as voltage, nozzle-to-collector distance and feeding rate on nanofbers morphology, were also checked by the scanning electron microscopy images. After changing the parameters on diferent steps, designed by the chemo metrics software, the fnest nanofbers were produced in the following conditions: 2% kefran concentration, 30/70 kefran/polymer mixing ratio, 12 kV voltage, 200 mm needle-to-collector distance and 0.5 (mL/h) polymer injection rate. The nanofbers produced in these conditions were uniform without knots or adhesion in the lowest diameter of 156 nm. Kefran concentration and kefran/polymer mixing ratio were found as the most efective parameter in the morphology and diameter size of the nanofbers. The attenuated total refectance (ATR-Ft-IR), atomic force spectroscopy, diferential scanning calorimeters and thermal gravimetric analysis were used to investigate molecular structures, threedimensional morphology and heating properties of the nanofbers, respectively.
Keywords: Poly(vinyl alcohol), Poly(vinyl pyrrolidone), Kefran, Electrospinning, Composite nanofber
Application: Nanocomposite
Product Model 1: Electroris
Product Model 2:
URL: #https://link.springer.com/content/pdf/10.1007/s42452-020-2714-3.pdf#